The researchers discovered that, as antibiotics, platensimycin and platencin thiocarboxylic acids appeared to bind to their biological targets even better than their carboxylic acid counterparts.The researchers revealed, for the first time, the exact genes, and the enzymes they encode, that bacteria use to create thiocarboxylic acids.

The study is published in Nature Communications.After this, the scientists set out to test whether nature-made thiocarboxylic acids could also act as biological warheads as well."There are many, many thiocarboxylic acid natural products waiting to be discovered, making them a treasure trove of potential new drug leads or drugs" said Shen. Representational Image.Interestingly, thiocarboxylic acids appeared to have been hiding in plain sight.Professor and co-chair of the Department of Chemistry at Scripps Research, Shen said,"We use natural products as an inspiration for chemistry, biology and drug discovery."Thiocarboxylic acids caught Shen&China auto rubber Manufacturers, Maharashtra76281076323 Gujarat3071282133 Delhi262586954 Rajasthan208351334 Madhya Pradesh194528199 Tamil Nadu182196023 Uttar Pradesh179326127 Andhra Pradesh101617131 Telangana99030725 West Bengal57110318 Karnataka50015818 Jammu and Kashmir4941126 Kerala4583384 Punjab3087217 Haryana2871913 Bihar251452 Odisha100341 Jharkhand6783 Uttarakhand48260 Himachal Pradesh40232 Chhatisgarh37320 Assam36191 Chandigarh28150 Meghalaya1201 Puducherry840 Goa770 Manipur220 Tripura220 Mizoram100 Arunachal Pradesh110 Life, Health Potential disease-fighting 'warheads' may be hidden in bacteria ANI Published: Jun 19, 2018, 2:13 pm IST Updated: Jun 19, 2018, 2:13 pm IST Here is what a new study has found.

The findings done by Ben Shen, PhD, and his colleagues at the Florida campus of Scripps Research investigated "natural products" made by organisms such as soil-dwelling bacteria.Shen and his colleagues then took a closer look at two natural products, platensimycin and platencin, that have been extensively investigated as potential antibiotics. (Photo: Pixabay) # Washington: The bacteria found in soil may harbor a potential game-changer for drug design, a study has found. The molecules were thought to be rare and were not much appreciated to date as a family of natural products.A new study by Scripps Research suggested that scientists could build better drugs by learning from molecules derived from bacteria called thiocarboxylic acids. To their surprise, platensimycin and platencin, are actually made by bacteria as thiocarboxylic acids

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The cream-colored polyamide material extends out from the torso in ridged loops, and thin strips of acrylic stick out from the waist of a matching short leather skirt in a way that mimics water squirting out from a fountain. "Often I'm inspired by things that are invisible to us, like magnetic motion or electricity."Often my inspiration doesn't come from something visual,” she said.Van Herpen, 31, said people sometimes assume she is inspired by technology, but that is not the case. Luckily, a video in a side gallery showcases six of her runway shows so visitors can see the outfits on models and watch the extraordinary way they move.

There are samples of six materials from outfits in the exhibition, including the ice dress and water dress, both of which are made from hard, unforgiving plastic, as well as a rubber material that feels like the skin of a Halloween mask, a fine wire mesh that is surprisingly flexible and a mat of fastened-together umbrella ribs..And though van Herpen's name may not be well-known to the average fashion-loving consumer, fashion-forward singers like Lady Gaga, Bjork and Beyonce have all worn her creations. Once she has an idea in her head she experiments to see whether it can best be executed by hand or using more high-tech methods, like 3-D printing. wholesale Rubber gasket Drawing inspiration from sources including art, architecture, the movement of the human body and science, Iris van Herpen creates cutting-edge fashion using a combination of traditional craftsmanship 10TECHANCHOR.The result is a stunning short strapless dress that hinges open along one side and snaps onto the model.

The pieces are displayed on custom mannequins in such a way that visitors can walk around and see them from every angle because they are as much sculpture as clothing, said High curator of decorative arts and design Sarah Schleuning. It looks like a delicately carved ice sculpture.”Her creative process often includes collaborations with other artists, designers, architects and scientists. The structures are so fine and delicate that the technicians at the company that printed it for her initially didn't think it would be possible to create with a 3-D printer using the transparent resin she wanted.

The first 3-D printed piece she sent down a runway was from a collection called Crystallization in July 2010 and was inspired by the way limestone deposits harden.One of the most remarkable pieces in the exhibition, which the High recently acquired, is from van Herpen's spring 2015 collection, Magnetic Motion.

Rather she sees technology as a tool to help her achieve the physical representation of ideas in her head, she said.In the same collection is a water-inspired dress. A simple iridescent beige leather sheath with columns of ruffles and draped in metal chains is accented by a giant plastic collar that makes it look as if someone came up and threw a bucket of water on the model and that splash is frozen in time. Like many of the other pieces in the exhibition, it's hard to imagine how it looks on a human body."Iris van Herpen: Transforming Fashion,” a new exhibition opening Saturday at Atlanta's High Museum of Art, features 45 pieces pulled from 15 of the Dutch artist's collections designed between 2008 and this year.Made from materials that include woven metal gauze, the metal ribs of children's umbrellas, leather, laser-cut acrylic, foil, stones, cotton and more, the dresses scream to be touched, and the High is happy to oblige. Organized chronologically, it gives visitors insight into the evolution of the young designer's career.Many of the couture pieces look like costumes from a futuristic science fiction movie, with dramatic flourishes created from unexpected materials and contrasting textures

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But these are not things I can say about myself.Shahbaz Taseer said that the Islamic Movement of Uzbekistan was seeking a huge ransom and the release of 25 fighters — demands that could never be met. I bled for seven days and they didn’t give me any help for seven days."For example, they pulled my fingernails out — it started off with them lashing me with rubber whips.”

Mr Taseer, who is in his early 30s, described his survival as a "personal victory”.According to Shahbaz his new captors were not interested in a ransom, but instead "sentenced” him to further jail time, before, adding, "I met someone there who helped release me.”. Critics say these are routinely used to persecute minorities.Salmaan’s death made him a liberal icon and put his family in the crosshairs of Islamist militants who have been waging an insurgency against the state since 2004. They shot me in my leg. They cut flesh off my back.However, Shahbaz Taseer, in his first interview since he returned home in March, said he never abandoned hope that he would one day see his family again.He said that his kidnapping was orchestrated by the Islamic Movement of Uzbekistan — a group associated with Al Qaeda which is blamed for high-profile terror attacks in Pakistan, including the 2014 storming of Karachi airport.

The son of a murdered Pakistani governor has described in chilling detail Grommet Factory how he was flogged, shot and had his nails pulled out by Islamic militants during almost five years in captivity."I was tortured for about a year in these extravagant Hollywood-style movies they would make for my family to put pressure on them, pressure on the government,” Mr Taseer told CNN on Tuesday.”Prior to Mr Taseer’s account, few details were known about his capture or time in detention. But in 2015 conflict broke out between it and the Afghan Taliban, who took custody of Taseer after defeating the Uzbeks. What I can say about myself is that I learnt to be very patient.

They would carve my back open with blades and throw salt and sewed my mouth shut and starved me for a week.Mr Taseer, who was kidnapped in his home town of Lahore in 2011, described his horrific ordeal in Pakistan’s tribal areas and in Afghanistan in interviews with the BBC’s Urdu service and CNN."People, friends and family say you are very brave, you came back, it was very heroic. His father Salmaan Taseer was governor of Punjab province, but had been shot dead just months earlier by his own bodyguard for his opposition to the country’s blasphemy laws. He said patience and the hope of eventual release sustained him.

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"We are watching the situation very carefully but to say that we are worried at this time, I think will not be correct.Replying to queries about rising trade tensions, Kumar said the whole economy has got used to open economy framework and that the trade war, which was started by the US, would add to the turbulence.Niti Aayog Vice Chairman Rajiv Kumar said subsidy should be applicable for all fuels that are used for cooking.He said oil prices have risen but now are stable and are not rising anymore."Niti Aayog is working on a proposal to replace LPG subsidy with cooking subsidy.2 kilogram each per household in a year by directly transferring the subsidy amount to the users&China wholesale silicone rubber39; bank accounts. However, the government subsidises 12 cylinders of 14."(For) all fuels which are used for cooking, subsidy should be applicable.However, the Niti Aayog Vice Chairman that if the trade war between the US and China leads to greater turbulence, then India should be prepared for that.

"We are not worried simply because there is enough space for our exports to be increases. Govt to replace LPG subsidy with cooking subsidy in order to extend the benefits to people using piped natural gas and biofuels for cooking purposes."I think the worst is over.Government think tank Niti Aayog is working on a proposal to replace LPG subsidy with cooking subsidy in order to extend the benefits to people using piped natural gas and biofuels for cooking purposes, a top official said today. Because trade war is not directed against India not so far," Kumar said. when you look at six months future, prices have slightly declined, not rising that's a big comfort," he added...After inter-ministerial consultations, the policy would be taken up by the Cabinet. LPG is a specific product, a subsidy should be for larger set of all products/ fuels which are used for cooking. Also inflation, we have seen that core inflation is higher than headline inflation.

Some of the nations have responded back by slapping tariffs on American products.There is looming threat of intensified trade war with the US imposing tariffs on products from various countries, including China, Russia and India.5 per cent this fiscal year".At present, the government extends subsidy to users of Liquefied Petroleum Gas (LPG). "

Because if there are some cities where PNG (Piped Natural Gas) is used, then it is only logical that the subsidy be extended to them also," Kumar told PTI in an interview.Noting that India's macro conditions are very good very strong, Kumar said, "I think, despite some sluggishness in private investments, we will surely grow at 7-7.Kumar's comments also # come against the backdrop of apprehensions in certain quarters that subsidy only for LPG users is inhibiting the adoption of clean and cheap fuels such as biofuels in rural areas and PNG in urban areas.2 kg each per household in a year by directly transferring subsidy amount to the users' bank accounts."So, I think it is on external account that we need to do much better and there we will have a focused approach," he said. The draft was made public last year.The changes pertaining to cooking subsidy are likely to be incorporated in the draft National Energy Policy 2030.Kumar, who himself is a noted economist, admitted that a little cause of worry was that out merchandise trade exports were not rising and that invisible trade exports have not performed well.All LPG consumers have to buy fuel at market price. Fuel and food are not contributing to inflation, so this will also tend to weaken as supplies improve," he said

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