The researchers discovered that, as antibiotics, platensimycin and platencin thiocarboxylic acids appeared to bind to their biological targets even better than their carboxylic acid counterparts.The researchers revealed, for the first time, the exact genes, and the enzymes they encode, that bacteria use to create thiocarboxylic acids.

The study is published in Nature Communications.After this, the scientists set out to test whether nature-made thiocarboxylic acids could also act as biological warheads as well."There are many, many thiocarboxylic acid natural products waiting to be discovered, making them a treasure trove of potential new drug leads or drugs" said Shen. Representational Image.Interestingly, thiocarboxylic acids appeared to have been hiding in plain sight.Professor and co-chair of the Department of Chemistry at Scripps Research, Shen said,"We use natural products as an inspiration for chemistry, biology and drug discovery."Thiocarboxylic acids caught Shen&China auto rubber Manufacturers, Maharashtra76281076323 Gujarat3071282133 Delhi262586954 Rajasthan208351334 Madhya Pradesh194528199 Tamil Nadu182196023 Uttar Pradesh179326127 Andhra Pradesh101617131 Telangana99030725 West Bengal57110318 Karnataka50015818 Jammu and Kashmir4941126 Kerala4583384 Punjab3087217 Haryana2871913 Bihar251452 Odisha100341 Jharkhand6783 Uttarakhand48260 Himachal Pradesh40232 Chhatisgarh37320 Assam36191 Chandigarh28150 Meghalaya1201 Puducherry840 Goa770 Manipur220 Tripura220 Mizoram100 Arunachal Pradesh110 Life, Health Potential disease-fighting 'warheads' may be hidden in bacteria ANI Published: Jun 19, 2018, 2:13 pm IST Updated: Jun 19, 2018, 2:13 pm IST Here is what a new study has found.

The findings done by Ben Shen, PhD, and his colleagues at the Florida campus of Scripps Research investigated "natural products" made by organisms such as soil-dwelling bacteria.Shen and his colleagues then took a closer look at two natural products, platensimycin and platencin, that have been extensively investigated as potential antibiotics. (Photo: Pixabay) # Washington: The bacteria found in soil may harbor a potential game-changer for drug design, a study has found. The molecules were thought to be rare and were not much appreciated to date as a family of natural products.A new study by Scripps Research suggested that scientists could build better drugs by learning from molecules derived from bacteria called thiocarboxylic acids. To their surprise, platensimycin and platencin, are actually made by bacteria as thiocarboxylic acids

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